Updated on 2010.1.6

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P A P E R S
  1. Redox Behavior of Active Aldehydes Derived from Thiamin Coenzyme Analogs
    Ikuo Nakanishi, Shinobu Itoh, Tomoyoshi Suenobu, Hiroo Inoue, and Shunichi Fukuzumi
    Chem. Lett., 26 (8), 707-708 (1997). DOI: 10.1246/cl.1997.707
  2. Electron Transfer Properties of Active Aldehydes Derived from Thiamin Coenzyme Analogues
    Ikuo Nakanishi, Shinobu Itoh, Tomoyoshi Suenobu, and Shunichi Fukuzumi
    Chem. Commun., 1997 (19), 1927-1928 (1997). DOI: 10.1039/a704559j
  3. Direct Observation of Radical Intermediates While Investigating the Redox Behavior of Thiamin Coenzyme Models
    Ikuo Nakanishi, Shinobu Itoh, Tomoyoshi Suenobu, and Shunichi Fukuzumi
    Angew. Chem., 110 (7), 1040-1042 (1998); Angew. Chem., Int. Ed., 37 (7), 992-994 (1998). DOI: 10.1002/(SICI)1521-3773(19980420)37:7<992::AID-ANIE992>3.0.CO;2-P
  4. Formation of Radical Anions in the Reaction of p-Benzoquinone and C60 with Alkoxide Anions
    Shunichi Fukuzumi, Ikuo Nakanishi, Junichi Maruta, Tomohiro Yorisue, Tomoyoshi Suenobu, Shinobu Itoh, Ryuichi Arakawa, and Karl M. Kadish
    J. Am. Chem. Soc., 120 (27), 6673-6680 (1998). DOI: 10.1021/ja980615k
  5. Electron-Transfer Kinetics for Generation of Organoiron(IV) Porphyrins and the Iron(IV) Porphyrin p Radical Cations
    Shunichi Fukuzumi, Ikuo Nakanishi, Keiko Tanaka, Tomoyoshi Suenobu, Alain Tabard, Roger Guilard, Eric Van Caemelbecke, and Karl M. Kadish
    J. Am. Chem. Soc., 121 (4), 785-790 (1999). DOI: 10.1021/ja982136r
  6. Decreased Electron Transfer Rates of Manganese Porphyrins with Conformational Distortions of the Macrocycle
    Shunichi Fukuzumi, Ikuo Nakanishi, Jean-Michel Barbe, Roger Guilard, Eric Van Caemelbecke, Ning Guo, and Karl M. Kadish
    Angew. Chem., 111 (7), 1017-1019 (1999); Angew. Chem., Int. Ed., 38 (7), 964-966 (1999). DOI: 10.1002/(SICI)1521-3773(19990401)38:7<964::AID-ANIE964>3.0.CO;2-O
  7. Electron-Transfer Properties of C60 and tert-Butyl-C60 Radical
    Shunichi Fukuzumi, Ikuo Nakanishi, Tomoyoshi Suenobu, and Karl M. Kadish
    J. Am. Chem. Soc., 121 (14), 3468-3474 (1999). DOI: 10.1021/ja9838615
  8. Synthesis and Electrochemical Studies of a Series of Fluorinated Dodecaphenylporphyrins
    Karl M. Kadish, Eric Van Caemelbecke, Francis D'Souza, Min Lin, Daniel J. Nurco, Craig J. Medforth, Timothy P. Forsyth, B始仕icte Krattinger, Kevin M. Smith, Shunichi Fukuzumi, Ikuo Nakanishi, and John A. Shelnutt
    Inorg. Chem., 38 (9), 2188-2198 (1999). DOI: 10.1021/ic9811695
  9. Electron-Transfer Properties of Active Aldehydes of Thiamin Coenzyme Models, and Mechanism of Formation of the Reactive Intermediates
    Ikuo Nakanishi, Shinobu Itoh, and Shunichi Fukuzumi
    Chem. Eur. J., 5 (10), 2810-2818 (1999). DOI: 10.1002/(SICI)1521-3765(19991001)5:10<2810::AID-CHEM2810>3.0.CO;2-F
  10. Migration Reactivities of s-Bonded Ligands of Organoiron and Organocobalt Porphyrins Depending on Different High Oxidation States
    Shunichi Fukuzumi, Ikuo Nakanishi, Keiko Tanaka, Alain Tabard, Roger Guilard, Eric Van Caemelbecke, and Karl M. Kadish
    Inorg. Chem., 38 (22), 5000-5006 (1999). DOI: 10.1021/ic990324s
  11. Multielectron Oxidation of Anthracenes with a One-Electron Oxidant via Water-Accelerated Electron-Transfer Disproportionation of the Radical Cations as the Rate-Determining Step
    Shunichi Fukuzumi, Ikuo Nakanishi, and Keiko Tanaka
    J. Phys. Chem. A, 103 (50), 11212-11220 (1999). DOI: 10.1021/jp990541e
  12. Base Control of Electron-Transfer Reactions of Manganese(III) Porphyrins
    Ikuo Nakanishi, Shunichi Fukuzumi, Jean-Michel Barbe, Roger Guilard, and Karl M. Kadish
    Eur. J. Inorg. Chem., 2000 (7), 1557-1562 (2000). DOI: 10.1002/1099-0682(200007)2000:7<1557::AID-EJIC1557>3.0.CO;2-9
  13. Hydroxylation of Nitrated Naphthalenes with KO2/Crown Ether
    Kiyoshi Fukuhara, Yukie Hara, Ikuo Nakanishi, and Naoki Miyata
    Chem. Pharm. Bull., 48 (10), 1532-1535 (2000).
  14. Reactive Species Responsible for Biological Actions of Photoexcited Fullerenes
    Naoki Miyata, Yoko Yamakoshi, and Ikuo Nakanishi
    Yakugaku Zasshi, 120 (10), 1007-1016 (2000).
  15. DNA Damage Caused by Photosensitizers
    Ikuo Nakanishi and Naoki Miyata
    Environ. Mutagen Res., 23 (2), 65-71 (2001).
  16. Superoxide Anion Generation via Electron-Transfer Oxidation of Catechin Dianion by Molecular Oxygen in an Aprotic Medium
    Ikuo Nakanishi, Kiyoshi Fukuhara, Kei Ohkubo, Tomokazu Shimada, Hisao Kansui, Masaaki Kurihara, Shiro Urano, Shunichi Fukuzumi, and Naoki Miyata
    Chem. Lett., 30 (11), 1152-1153 (2001). DOI: 10.1246/cl.2001.1152
  17. DNA Cleavage via Superoxide Anion Formed in Photoinduced Electron Transfer from NADH to g-Cyclodextrin-Bicapped C60 in an Oxygen-Saturated Aqueous Solution
    Ikuo Nakanishi, Shunichi Fukuzumi, Toshifumi Konishi, Kei Ohkubo, Mamoru Fujitsuka, Osamu Ito, and Naoki Miyata
    J. Phys. Chem. B, 106 (9), 2372-2380 (2002). DOI: 10.1021/jp013215j
  18. Enhanced Radical-Scavenging Activity of a Planar Catechin Analogue
    Kiyoshi Fukuhara, Ikuo Nakanishi, Hisao Kansui, Etsuko Sugiyama, Mitsuhiro Kimura, Tomokazu Shimada, Shiro Urano, Kentaro Yamaguchi, and Naoki Miyata
    J. Am. Chem. Soc., 124 (21), 5952-5953 (2002). DOI: 10.1021/ja0178259
  19. Effects of Magnesium Ion on Kinetic Stability and Spin Distribution of Phenoxyl Radical Derived from a Vitamin E Analogue: Mechanistic Insight into Antioxidative Hydrogen Transfer Reaction of Vitamin E
    Ikuo Nakanishi, Kiyoshi Fukuhara, Tomokazu Shimada, Kei Ohkubo, Yuko Iizuka, Keiko Inami, Masataka Mochizuki, Shiro Urano, Shinobu Itoh, Naoki Miyata, and Shunichi Fukuzumi
    J. Chem. Soc., Perkin Trans. 2, 2002 (9), 1520-1524 (2002). DOI: 10.1039/b205380b
  20. Direct Detection of Superoxide Anion Generated in C60-Photosensitized Oxidation of NADH and an Analogue by Molecular Oxygen
    Ikuo Nakanishi, Kei Ohkubo, Shunsuke Fujita, Shunichi Fukuzumi, Toshifumi Konishi, Mamoru Fujitsuka, Osamu Ito, and Naoki Miyata
    J. Chem. Soc., Perkin Trans. 2, 2002 (11), 1829-1833 (2002). DOI: 10.1039/b206887g
  21. Effects of Metal Ions Distinguishing between One-Step Hydrogen- and Electron-Transfer Mechanisms for the Radical-Scavenging Reaction of (+)-Catechin
    Ikuo Nakanishi, Kentaro Miyazaki, Tomokazu Shimada, Kei Ohkubo, Shiro Urano, Nobuo Ikota, Toshihiko Ozawa, Shunichi Fukuzumi, and Kiyoshi Fukuhara
    J. Phys. Chem. A, 106 (46), 11123-11126 (2002). DOI: 10.1021/jp026190c
  22. A Planar Catechin Analogue as a Promising Antioxidant with Reduced Prooxidant Activity
    Kiyoshi Fukuhara, Ikuo Nakanishi, Tomokazu Shimada, Kei Ohkubo, Kentaro Miyazaki, Wataru Hakamata, Shiro Urano, Nobuo Ikota, Toshihiko Ozawa, Haruhiro Okuda, Naoki Miyata, and Shunichi Fukuzumi
    Chem. Res. Toxicol., 16 (1), 81-86 (2003). DOI: 10.1021/tx025581f
  23. Efficient Radical Scavenging Ability of Artepillin C, a Major Component of Brazilian Propolis, and the Mechanism
    Ikuo Nakanishi, Yoshihiro Uto, Kei Ohkubo, Kentaro Miyazaki, Haruko Yakumaru, Shiro Urano, Haruhiro Okuda, Jun-Ichi Ueda, Toshihiko Ozawa, Kiyoshi Fukuhara, Shunichi Fukuzumi, Hideko Nagasawa, Hitoshi Hori, and Nobuo Ikota
    Org. Biomol. Chem., 1 (9), 1452-1454 (2003). DOI: 10.1039/b302098c
  24. Kinetic Study of the Electron-Transfer Oxidation of the Phenolate Anion of a Vitamin E Model by Molecular Oxygen Generating Superoxide Anion in an Aprotic Medium
    Ikuo Nakanishi, Kentaro Miyazaki, Tomokazu Shimada, Yuko Iizuka, Keiko Inami, Masataka Mochizuki, Shiro Urano, Haruhiro Okuda, Toshihiko Ozawa, Shunichi Fukuzumi, Nobuo Ikota, and Kiyoshi Fukuhara
    Org. Biomol. Chem., 1 (22), 4085-4088 (2003). DOI: 10.1039/b306758k
  25. A Planar Catechin Analogue Having a More Negative Oxidation Potential than (+)-Catechin as an Electron-Transfer Antioxidant against a Peroxyl Radical
    Ikuo Nakanishi, Kei Ohkubo, Kentaro Miyazaki, Wataru Hakamata, Shiro Urano, Toshihiko Ozawa, Haruhiro Okuda, Shunichi Fukuzumi, Nobuo Ikota, and Kiyoshi Fukuhara
    Chem. Res. Toxicol., 17 (1), 26-31 (2004). DOI: 10.1021/tx034134c
  26. EPR Study on Stable Magnesium Complexes of the Phenoxyl Radicals Derived from a Vitamin E Model and Its Deuterated Derivatives
    Ikuo Nakanishi, Shigenobu Matsumoto, Kei Ohkubo, Kiyoshi Fukuhara, Haruhiro Okuda, Keiko Inami, Masataka Mochizuki, Toshihiko Ozawa, Shinobu Itoh, Shunichi Fukuzumi, and Nobuo Ikota
    Bull. Chem. Soc. Jpn., 77 (9), 1741-1744 (2004). DOI: 10.1246/bcsj.77.1741
  27. Water-Accelerated Radical-Scavenging Reaction of (+)-Catechin in an Aprotic Medium
    Ikuo Nakanishi, Tomonori Kawashima, Kiyoshi Fukuhara, Hideko Kanazawa, Haruhiro Okuda, Shunichi Fukuzumi, Toshihiko Ozawa, and Nobuo Ikota
    ITE Lett. Batt. New Tech. Med., 5 (6), 585-588 (2004).
  28. Electron-Tansfer Mechanism in Radical-Scavenging Reactions by a Vitamin E Model in a Protic Medium
    Ikuo Nakanishi, Tomonori Kawashima, Kei Ohkubo, Hideko Kanazawa, Keiko Inami, Masataka Mochizuki, Kiyoshi Fukuhara, Haruhiro Okuda, Toshihiko Ozawa, Shinobu Itoh, Shunichi Fukuzumi, and Nobuo Ikota
    Org. Biomol. Chem., 3 (4), 626-629 (2005). DOI: 10.1039/b416572a
  29. Hydroxyl Radical Generation via Photoreduction of a Simple Pyridine N-Oxide by an NADH Analogue
    Ikuo Nakanishi, Chiho Nishizawa, Kei Ohkubo, Keizo Takeshita, Kazuo T. Suzuki, Toshihiko Ozawa, Sidney M. Hecht, Masayuki Tanno, Shoko Sueyoshi, Naoki Miyata, Haruhiro Okuda, Shunichi Fukuzumi, Nobuo Ikota, and Kiyoshi Fukuhara
    Org. Biomol. Chem., 3 (18), 3263-3265 (2005). DOI: 10.1039/b509447j
  30. Structural Basis for DNA-Cleaving Activity of Resveratrol in the Presence of Cu(II)
    Kiyoshi Fukuhara, Maki Nagakawa, Ikuo Nakanishi, Kei Ohkubo, Kohei Imai, Shiro Urano, Shunichi Fukuzumi, Toshihiko Ozawa, Nobuo Ikota, Masataka Mochizuki, Naoki Miyata, and Haruhiro Okuda
    Bioorg. Med. Chem., 14 (5), 1437-1443 (2006). DOI: 10.1016/j.bmc.2005.09.070
  31. Reaction of para-Hydroxybenzoic Acid Esters with Singlet Oxygen in the Presence of Glutathione Produces Glutathione Conjugates of Hydroquinone, Potent Inducers of Oxidative Stress
    Chiho Nishizawa, Keizo Takeshita, Jun-Ichi Ueda, Ikuo Nakanishi, Kazuo T. Suzuki, and Toshihiko Ozawa
    Free Radical Res., 40 (3), 233-240 (2006). DOI: 10.1080/10715760500485036
  32. Comparison of Stable Nitroxide, 3-Substituted 2,2,5,5-Tetramethylpyrrolidine-N-oxyls, with Respect to Protection from Radiation, Prevention of DNA Damage, and Distribution in Mice
    Kazunori Anzai, Megumi Ueno, Akira Yoshida, Masako Furuse, Winn Aung, Ikuo Nakanishi, Takashi Moritake, Keizo Takeshita, and Nobuo Ikota
    Free Radical Biol. Med., 40 (7), 1170-1178 (2006). DOI: 10.1016/j.freeradbiomed.2005.11.006
  33. Planar Catechin Analogues with Alkyl Side Chains, a Potent Antioxidant and an a-Glucosidase Inhibitor
    Wataru Hakamata, Ikuo Nakanishi, Yu Masuda, Takehiko Shimizu, Hajime Higuchi, Yuriko Nakamura, Shinichi Saito, Shiro Urano, Tadatake Oku, Toshihiko Ozawa, Nobuo Ikota, Naoki Miyata, Haruhiro Okuda, and Kiyoshi Fukuhara
    J. Am. Chem. Soc., 128 (20), 6524-6525 (2006). DOI: 10.1021/ja057763c
  34. Drastic Effect of Several Caffeic Acid Derivatives on the Induction of Heme Oxygenase-1 Expression Revealed by Quantitative Real-Time RT-PCR
    Keiko Suzuki, Izumi Tanaka, Ikuo Nakanishi, Ayako Kurematsu, Haruko Yakumaru, Nobuo Ikota, and Hiroshi Ishihara
    Biofactors, 28 (3-4), 151-158 (2006).
  35. Scandium Ion-Accelerated Scavenging Reaction of Cumylperoxyl Radical by a Cyclic Nitroxyl Radical via Electron Transfer
    Ikuo Nakanishi, Kumiko Kawaguchi, Kei Ohkubo, Tomonori Kawashima, Sushma Manda, Hideko Kanazawa, Keizo Takeshita, Kazunori Anzai, Toshihiko Ozawa, Shunichi Fukuzumi, and Nobuo Ikota
    Chem. Lett., 36 (3), 378-379 (2007). DOI: 10.1246/cl.2007.378
  36. Effect of Solvent Polarity on the One-Electron Oxidation of Cyclic Nitroxyl Radicals
    Sushma Manda, Ikuo Nakanishi, Kei Ohkubo, Tomonori Kawashima, Ken-ichiro Matsumoto, Toshihiko Ozawa, Shunichi Fukuzumi, Nobuo Ikota, and Kazunori Anzai
    Chem. Lett., 36 (7), 914-915 (2007). DOI: 10.1246/cl.2007.914
  37. A Long-Lived o-Semiquinone Radical Anion is Formed from N-b-alanyl-5-S-glutathionyl-3,4-dihydroxyphenylalanine (5-S-GAD), an Insect-derived Antibacterial Substance
    Nobuko Akiyama, Ikuo Nakanishi, Kei Ohkubo, Kazue Satoh, Koichiro Tsuchiya, Takeshi Nishikawa, Shunichi Fukuzumi, Nobuo Ikota, Toshihiko Ozawa, Masafumi Tsujimoto, and Shunji Natori
    J. Biochem., 142 (1), 41-48 (2007). DOI: 10.1093/jb/mvm101
  38. Involvement of Electron Transfer in the Radical-Scavenging Reaction of Resveratrol
    Ikuo Nakanishi, Tomokazu Shimada, Kei Ohkubo, Sushma Manda, Takehiko Shimizu, Shiro Urano, Haruhiro Okuda, Naoki Miyata, Toshihiko Ozawa, Kazunori Anzai, Shunichi Fukuzumi, Nobuo Ikota, and Kiyoshi Fukuhara
    Chem. Lett., 36 (10), 1276-1277 (2007). DOI: 10.1246/cl.2007.1276
  39. Nitroxyl Radicals: Electrochemical Redox Behaviour and Structure-Activity Relationships
    Sushma Manda, Ikuo Nakanishi, Kei Ohkubo, Haruko Yakumaru, Ken-ichiro Matsumoto, Toshihiko Ozawa, Nobuo Ikota, Shunichi Fukuzumi, and Kazunori Anzai
    Org. Biomol. Chem., 5 (24), 3951-3955 (2007). DOI: 10.1039/b714765a
    OBC Inside Cover
  40. Enhanced Radical-Scavenging Activity of Naturally-Oriented Artepillin C Derivatives
    Sushma Manda, Ikuo Nakanishi, Kei Ohkubo, Yoshihiro Uto, Tomonori Kawashima, Kiyoshi Fukuhara, Haruhiro Okuda, Hitoshi Hori, Toshihiko Ozawa, Nobuo Ikota, Shunichi Fukuzumi, and Kazunori Anzai
    Chem. Commun., 2008 (5), 626-628. DOI: 10.1039/b715973k
  41. Effect of Methyl Substitution on Antioxidative Property and Genotoxicity of Resveratrol
    Kiyoshi Fukuhara, Ikuo Nakanishi, Atsuko Matsuoka, Tomohiro Matsumura, Sachiko Honda, Mikiko Hayashi, Toshihiko Ozawa, Naoki Miyata, Shinichi Saito, Nobuo Ikota, and Haruhiro Okuda
    Chem. Res. Toxicol., 21 (2), 282-287 (2008). DOI: 10.1021/tx7003008
  42. Intracellular and Extracellular Redox Environments Surrounding Redox-Sensitive Contrast Agents under Oxidative Atmosphere
    Aya Okajo, Iori Ui, Sushma Manda, Ikuo Nakanishi, Ken-ichiro Matsumoto, Kazunori Anzai, and Kazutoyo Endo
    Biol. Pharm. Bull., 32 (4), 535-541 (2009).
  43. Detection of Free Radical Reactions in an Aqueous Sample Induced by Low Linear-Energy-Transfer Irradiation
    Ken-ichiro Matsumoto, Aya Okajo, Katsura Nagata, William G. DeGraff, Minako Nyui, Megumi Ueno, Ikuo Nakanishi, Toshihiko Ozawa, James B. Mitchell, Murari C. Krishna, Haruhiko Yamamoto, Kazutoyo Endo, and Kazunori Anzai
    Biol. Pharm. Bull., 32 (4), 542-547 (2009).
  44. Intramolecular Base-Accelerated Radical-Scavenging Reaction of a Planar Catechin Derivative Bearing a Lysine Moiety
    Kiyoshi Fukuhara, Ikuo Nakanishi, Kei Ohkubo, Yoshinori Obara, Ayako Tada, Kohei Imai, Akiko Ohno, Asao Nakamura, Toshihiko Ozawa, Shiro Urano, Shinichi Saito, Shunichi Fukuzumi, Kazunori Aznai, Naoki Miyata, and Haruhiro Okuda
    Chem. Commun., 2009 (41), 6180-6182. DOI: 10.1039/b913714a.
  45. Novel Ninhydrin Adduct of Catechin with Potent Antioxidative Activity
    Kiyoshi Fukuhara, Akiko Ohno, Ikuo Nakanishi, Kohei Imai, Asao Nakamura,Kazunori Aznai, Naoki Miyata, and Haruhiro Okuda
    Tetrahedron Lett., 50 (50), 6989-6992 (2009). DOI: 10.1016/j.tetlet.2009.09.149
  46. Visualizing Distribution of Hydrogen Peroxide in an Aqueous Gelatin Sample Irradiated by Carbon Ion Beam
    Ken-ichiro Matsumoto, Ikuo Nakanishi, Kazunori Anzai, et al.
    Radiat. Res., in contribution.
  47. Kinetics and Mechanism of DPPH Radical-Scavenging by Synthetic Artepillin C Derivatives
    Ikuo Nakanishi, Sushma Manda, Kei Ohkubo, Yoshihiro Uto, Tomonori Kawashima, Hitoshi Hori, Kiyoshi Fukuhara, Haruhiro Okuda, Toshihiko Ozawa, Nobuo Ikota, Shunichi Fukuzumi, and Kazunori Anzai
    Org. Bioimol. Chem., in preparation.
  48. Synthesis and Antioxidative Activity of Vitamin E Analogs Substituted with Chloro Goup on the Chroman Ring
    Keiko Inami, Yuko Iizuka, Miyuki Furukawa, Ikuo Nakanishi, Kiyoshi Fukuhara, Kazunori Anzai, Haruhiro Okuda, and Masataka Mochizuki
    Bioorg. Med. Chem., in preparation.
  49. Detection of Phenoxyl Radicals Derived from Aminochromanols in Aqueous Solution
    Keiko Inami, Ikuo Nakanishi, Mine Morita, Miyuki Furukawa, Yuko Iizuka, Kei Ohkubo, Kazunori Anzai, Shunichi Fukuzumi, and Masataka Mochizuki
    J. Am. Chem. Soc., in preparation.
  50. Electrochemical Redox Behaviour of Antioxidative Dihydropyridine Derivatives
    Masato Kamibayashi, Ikuo Nakanishi, Kei Ohkubo, Tomonori Kawashima, Ikuo Kawasaki, Masayuki Yamashita, Shunsaku Ohta, Nobuo Ikota, Shunichi Fukuzumi, Toshihiko Ozawa, and Kazunori Anzai
    Chem. Lett., in preparation.
B O O K S
  1. Research Guide for First Year Graduate Students. The Basics of Giving a Research Presentation
    Ikuo Nakanishi
    Kagaku, 52 (4), 20-22 (1997).
  2. Formation of C60 Radical Anion in the Reaction of C60 with Alkoxide Anions
    Shunichi Fukuzumi, Ikuo Nakanishi, Junichi Maruta, Tomoyoshi Suenobu, Ryuichi Arakawa, and Karl M. Kadish
    "Fullerenes Volume 5: Recent Advances in the Chemistry and Physics of Fullerenes and Related Materials," ed by K. M. Kadish and R. S. Ruoff, The Electrochemical Society, Pennington, NJ (1997), pp.20-32.
  3. Electron Transfer Properties of C60 and the Alkyl Adduct Anion
    Shunichi Fukuzumi, Ikuo Nakanishi, Tomoyoshi Suenobu, and Karl M. Kadish
    "Fullerenes Volume 6: Recent Advances in the Chemistry and Physics of Fullerenes and Related Materials," ed by K. M. Kadish and R. S. Ruoff, The Electrochemical Society, Pennington, NJ (1998), pp.1263-1275.
  4. O2･- Generation in C60-Photosensitized Oxidation of NADH and an Analogue by Oxygen
    Ikuo Nakanishi, Yoko Yamakoshi, Kei Ohkubo, Shunsuke Fujita, Mamoru Fujitsuka, Osamu Ito, Shunichi Fukuzumi, and Naoki Miyata
    "Fullerenes 2000 Volume 8: Electrochemistry and Photochemistry," ed by S. Fukuzumi, F. D'Souza, and D. M. Guldi, The Electrochemical Society, Pennington, NJ (2000), pp.242-255.
  5. DNA Cleavage via Electron Transfer from NADH to Molecular Oxygen Photoinduced by g-Cyclodextrin-Bicapped C60
    Ikuo Nakanishi, Shunichi Fukuzumi, Toshifumi Konishi, Kei Ohkubo, Mamoru Fujitsuka, Osamu Ito, and Naoki Miyata
    "Fullerenes Volume 11: Fullerenes for the New Millenium," ed by P. V. Kamat, D. M. Guldi, and K. M. Kadish, The Electrochemical Society, Pennington, NJ (2001), pp.138-151.
  6. Generation of Oxygen Radicals and DNA-Cleaving Ability in Quinone/NADH System
    Kiyoshi Fukuhara, Yuki Naito, Yukiko Sato, Ikuo Nakanishi, and Naoki Miyata
    Magnetic Resonance in Medicine, 13, 139-142 (2002).
  7. Mechanism of Generation of Reactive Oxygen Species and DNA Damage by Photosensitized Reactions of Fullerenes
    Ikuo Nakanishi
    Radiological Sciences, 45 (10), 322-326 (2002).
  8. Electron-Transfer Mechanism in Radical-Scavenging Reactions of Flavonoids
    Ikuo Nakanishi, Kentaro Miyazaki, Tomokazu Shimada, Kei Ohkubo, Wataru Hakamata, Shiro Urano, Haruhiro Okuda, Shunichi Fukuzumi, Kiyoshi Fukuhara, Nobuo Ikota, and Toshihiko Ozawa
    Free Radical Biol. Med., 33 (S2), S308-S309 (2002).
  9. Oxidation Potentials of Antioxidative Flavonoids and the Radical-Scavenging Abilities
    Ikuo Nakanishi, Kentaro Miyazaki, Kei Ohkubo, Shiro Urano, Jun-Ichi Ueda, Wataru Hakamata, Haruhiro Okuda, Toshihiko Ozawa, Shunichi Fukuzumi, Kiyoshi Fukuhara, and Nobuo Ikota
    Free Radical Biol. Med., 35 (S1), S43 (2003).
  10. Radical-Scavenging Reactions of 4-Hydroxycinnamic Acid Derivatives in the Presence of Metal Ions
    Ikuo Nakanishi, Yoshihiro Uto, Tomonori Kawashima, Haruko Yakumaru, Hideko Kanazawa, Toshiniko Ozawa, Hideko Nagasawa, Hitoshi Hori, and Nobuo Ikota
    J. Pharm. Soc. Jpn., 124 (Suppl. 1), 94 (2004).
  11. Effects of Metal Ions on the Stability of Oxygen and Nitrogen Radicals
    Ikuo Nakanishi, Tomonori Kawashima, Hideko Kanazawa, Kei Ohkubo, Kiyoshi Fukuhara, Toshiniko Ozawa, Shunichi Fukuzumi, and Nobuo Ikota
    J. Pharm. Soc. Jpn., 124 (Suppl. 1), 95 (2004).
  12. ESR Study on Stable Magnesium Complexes of the Phenoxyl Radicals Derived from a Vitamin E Model and Its Deuterated Derivatives
    Ikuo Nakanishi, Shigenobu Matsumoto, Kei Ohkubo, Kiyoshi Fukuhara, Haruhiro Okuda, Keiko Inami, Masataka Mochizuki, Shinobu Itoh, Shunichi Fukuzumi, Nobuo Ikota, and Toshihiko Ozawa
    Free Radical Biol. Med., 37 (S1), S40 (2004).
  13. Solvent Effect on the Mechanism of Radical-Scavenging Reactions of a Vitamin E Analogue
    Ikuo Nakanishi, Tomonori Kawashima, Kei Ohkubo, Hideko Kanazawa, Haruhiro Okuda, Toshihiko Ozawa, Shunichi Fukuzumi, Kiyoshi Fukuhara, and Nobuo Ikota
    Free Radical Biol. Med., 37 (S1), S39-S40 (2004).
  14. Radical-Scavenging Activities of Lipophilic Planar Catechin Derivatives
    Ikuo Nakanishi, Nobuo Ikota, Tomonori Kawashima, Haruko Yakumaru, Hideko Kanazawa, Haruhiro Okuda, Kazunori Anzai, Toshihiko Ozawa, and Kiyoshi Fukuhara
    Free Radical Biol. Med., 37 (S1), S40 (2004).
  15. Radical-Scavenging Reactions of a Vitamin E Analogue in the Presence of a Metal Ion
    Ikuo Nakanishi, Kentaro Miyazaki, Kei Ohkubo, Yuko Iizuka, Keiko Inami, Shiro Urano, Haruhiro Okuda, Masataka Mochizuki, Shunichi Fukuzumi, Kiyoshi Fukuhara, Toshihiko Ozawa, and Nobuo Ikota
    "Advances in the Research of Vitamin E Volume XI," Japanese Vitamin E Research Association, Japan (2005), pp.17-22.
  16. Oxidation Behavior of a Vitamin E Analogue Anion
    Ikuo Nakanishi, Kentaro Miyazaki, Kei Ohkubo, Wataru Hakamata, Shiro Urano, Haruhiro Okuda, Shunichi Fukuzumi, Kiyoshi FUkuhara, Toshihiko Ozawa, and Nobuo Ikota
    "Advances in the Research of Vitamin E Volume XI," Japanese Vitamin E Research Association, Japan (2005), pp.90-95.
  17. Catalysis of Metal Ions in Radical-Scavenging Reactions by Phenolic Antioxidants in Protic Solvents
    Tomonori Kawashima, Ikuo Nakanishi, Minako Nyui, Kumiko Kawaguchi, Kei Ohkubo, Hideko Kanazawa, Haruhiro Okuda, Kiyoshi Fukuhara, Shunichi Fukuzumi, Toshihiko Ozawa, and Nobuo Ikota
    J. Pharm. Soc. Jpn., 125 (Suppl. 1), 88 (2005).
  18. Solvent Effect on the Radical-Scavenging Mechanism of a Vitamin E Model
    Tomonori Kawashima, Ikuo Nakanishi, Hideko Kanazawa, Haruhiro Okuda, Kiyoshi Fukuhara, Toshihiko Ozawa, and Nobuo Ikota
    "Proceeding of the 4th Meeting of Society of the Study of AOB (Antioxidant Biofactor)," (2005), in press.
  19. Development of Safe and Strong Antioxidative Supplements
    Ikuo Nakanishi
    Science & Technology Journal, 14 (8), 48-49 (2005).
  20. Scavenging Reaction of a Peroxyl Radical by a Nitroxide Radical via Electron Transfer
    Toshihiko Ozawa, Kumiko Kawaguchi, Ikuo Nakanishi, Kei Ohkubo, Tomonori Kawashima, Hideko Kanazawa, Kazunori Anzai, Shunichi Fukuzumi, and Nobuo Ikota
    Lipid Peroxide Research, 29, 78 (2005).
  21. Base-Catalyzed Radical-Scavenging Reactions by Phenolic Antioxidants
    Tomonori Kawashima, Ikuo Nakanishi, Minako Nyui, Haruko Yakumaru, Kei Ohkubo, Hideko Kanazawa, Haruhiro Okuda, Shunichi Fukuzumi, Toshihiko Ozawa, Kiyoshi Fukuhara, and Nobuo Ikota
    Free Radical Biol. Med., 39 (S1), S33-S34 (2005).
  22. Scavenging Reaction of Cumylperoxyl Radical by Nitroxide Radicals via Electron Transfer
    Ikuo Nakanishi, Kumiko Kawaguchi, Kei Ohkubo, Tomonori Kawashima, Hideko Kanazawa, Kazunori Anzai, Shunichi Fukuzumi, Toshihiko Ozawa, and Nobuo Ikota
    Free Radical Biol. Med., 39 (S1), S38 (2005).
  23. Redox Behavior of Nitroxide Spin Probes in the Presence of Metal Ions
    Tomonori Kawashima, Ikuo Nakanishi, Kumiko Kawaguchi, Kei Ohkubo, Sushma Manda, Hideko Kanazawa, Kazunori Anzai, Shunichi Fukuzumi, Toshihiko Ozawa, and Nobuo Ikota
    J. Pharm. Soc. Jpn., 126 (Suppl. 1), P-14 (2006).
  24. Synthesis, Radical-Scavenging Activity, and Redox Behavior of Planar Catechin Derivatives
    Kiyoshi Fukuhara, Ikuo Nakanishi, Tomonori Kawashima, Ayako Tada, Haruko Yakumaru, Kei Ohkubo, Hideko Kanazawa, Shiro Urano, Haruhiro Okuda, Naoki Miyata, Kazunori Anzai, Toshihiko Ozawa, Shunichi Fukuzumi, and Nobuo Ikota
    Free Radical Res., 40 (S1), S97 (2006).
  25. Kinetic Study on the Radical-Scavenging Activity of Natural Antioxidants Having 4-Propenylphenol Structures
    Tomonori Kawashima, Ikuo Nakanishi, Kei Ohkubo, Yoshihiro Uto, Sushma Manda, Hideko Kanazawa, Kiyoshi Fukuhara, Haruhiro Okuda, Keiko Suzuki, Hideko Nagasawa, Hitoshi Hori, Kazunori Anzai, Toshihiko Ozawa, Shunichi Fukuzumi, and Nobuo Ikota
    Free Radical Res., 40 (S1), S102 (2006).
  26. Radical-Scavenging Activity of Nitroxide Radical as an Electron Donor
    Kumiko Kawaguchi, Ikuo Nakanishi, Kei Ohkubo, Tomonori Kawashima, Sushma Manda, Hideko Kanazawa, Keizo Takeshita, Kazunori Anzai, Toshihiko Ozawa, Shunichi Fukuzumi, and Nobuo Ikota
    Free Radical Res., 40 (S1), S165 (2006).
  27. Kinetic Study on the Radical-Scavenging Activity of Natural Antioxidants Having 4-Propenylphenol Structures
    Tomonori Kawashima, Ikuo Nakanishi, Kei Ohkubo, Yoshihiro Uto, Sushma Manda, Hideko Kanazawa, Kiyoshi Fukuhara, Haruhiro Okuda, Keiko Suzuki, Hideko Nagasawa, Hitoshi Hori, Kazunori Anzai, Toshihiko Ozawa, Shunichi Fukuzumi, and Nobuo Ikota
    "XIII Congress of the Society for Free Radical Research International," International Proceedings, Medimond, Italy (2006), pp.199-201.
  28. Radical-Scavenging Activity of Nitroxyl Radical as an Electron Donor
    Sushma Manda, Kumiko Kawaguchi, Kei Ohkubo, Tomonori Kawashima, Hideko Kanazawa, Keizo Takeshita, Kazunori Anzai, Toshihiko Ozawa, Shunichi Fukuzumi, Nobuo Ikota, and Ikuo Nakanishi
    "XIII Congress of the Society for Free Radical Research International," International Proceedings, Medimond, Italy (2006), pp.237-239.
  29. Scavenging Activity of Cumylperoxyl Radical by Artepillin C and Its Derivatives
    Ikuo Nakanishi, Yoshihiro Uto, Kei Ohkubo, Tomonori Kawashima, Sushma Manda, Hideko Kanazawa, Hideko Nagasawa, Hitoshi Hori, Haruhiro Okuda, Kiyoshi Fukuhara, Toshihiko Ozawa, Nobuo Ikota, Shunichi Fukuzumi, and Kazunori Anzai
    Lipid Peroxide Research, 30, 62 (2006).
  30. Radical-Scavenging Reactions of 4-Propenylphenol Derivatives
    Tomonori Kawashima, Ikuo Nakanishi, Kei Ohkubo, Yoshihiro Uto, Sushma Manda, Keiko Suzuki, Hideko Kanazawa, Kiyoshi Fukuhara, Haruhiro Okuda, Hideko Nagasawa, Hitoshi Hori, Kazunori Anzai, Toshihiko Ozawa, Nobuo Ikota, and Shunichi Fukuzumi
    Free Radical Biol. Med., 41 (S1), S23 (2006).
  31. DNA Cleaving-Activity of Water-Soluble C70 under Visible-Light Irradiation
    Ikuo Nakanishi, Kei Ohkubo, Tomonori Kawashima, Kumiko Kawaguchi, Minako Nyui, Mitsuko Takusagawa, Sushma Manda, Tomoyoshi Suenobu, Kiyoshi Fukuhara, Haruhiro Okuda, Hideko Kanazawa, Naoki Miyata, Toshihiko Ozawa, Kazunori Anzai, Shunichi Fukuzumi, and Nobuo Ikota
    Free Radical Biol. Med., 41 (S1), S66 (2006).
  32. Base Catalysis in Radical-Scavenging Reactions by a Vitamin E Analogue
    Ikuo Nakanishi, Tomonori Kawashima, Kei Ohkubo, Hideko Kanazawa, Keiko Inami, Masataka Mochizuki, Kiyoshi Fukuhara, Haruhiro Okuda, Toshihiko Ozawa, Shinobu Itoh, Shunichi Fukuzumi, and Nobuo Ikota
    "Advances in the Research of Vitamin E Volume XII," Japanese Vitamin E Research Association, Japan (2006), pp.11-16.
  33. Radical-Scavenging Activities of 4-Propenylphenol Derivatives and a Vitamin E model
    Tomonori Kawashima, Ikuo Nakanishi, Yoshihiro Uto, Kei Ohkubo, Hideko Kanazawa, Kiyoshi Fukuhara, Haruhiro Okuda, Hideko Nagasawa, Hitoshi Hori, Shunichi Fukuzumi, Toshihiko Ozawa, and Nobuo Ikota
    "Advances in the Research of Vitamin E Volume XII," Japanese Vitamin E Research Association, Japan (2006), pp.115-120.
  34. Enhanced Radical-Scavenging Activity of Artepillin C Derivatives
    Ikuo Nakanishi, Kei Ohkubo, Yoshihiro Uto, Tomonori Kawashima, Sushma Manda, Hideko Kanazawa, Hitoshi Hori, Kiyoshi Fukuhara, Haruhiro Okuda, Toshihiko Ozawa, Nobuo Ikota, Shunichi Fukuzumi, and Kazunori Anzai
    FASEB J., 21 (6), lb373 (2007).
  35. Effects of Bio-Related Metal Ions on the Radical-Scavenging Reactions by Curcumin
    Tomonori Kawashima, Ikuo Nakanishi, Kei Ohkubo, Sushma Manda, Kiyoshi Fukuhara, Haruhiro Okuda, Toshihiko Ozawa, Nobuo Ikota, Kazunori Anzai, and Shunichi Fukuzumi
    J. Pharm. Soc. Jpn., 127 (Suppl. 2), 76 (2007).
  36. Electron-Transfer Mechanism in the Radical-Scavenging Reaction of Resveratrol
    Ikuo Nakanishi, Tomokazu Shimada, Kei Ohkubo, Sushma Manda, Shiro Urano, Haruhiro Okuda, Naoki Miyata, Toshihiko Ozawa, Kazunori Anzai, Shunichi Fukuzumi, Nobuo Ikota, and Kiyoshi Fukuhara
    Free Radical Biol. Med., 43 (S1), S17 (2007).
  37. Intramolecular Base-Accelerated Radical-Scavenging Reaction of a Planar Catechin Derivative Having a Lysine Moiety
    Kiyoshi Fukuhara, Ikuo Nakanishi, Miki Obara, Kei Ohkubo, Tomonori Kawashima, Toshihiko Ozawa, Nobuo Ikota, Kazunori Anzai, Shunichi Fukuzumi, Naoki Miyata, Shinichi Saito, and Haruhiro Okuda
    Free Radical Biol. Med., 43 (S1), S96 (2007).
  38. Radical-Scavenging Rates of Biosynthetic Precursors of Vitamin E and Their Acyclic Analogues
    Ikuo Nakanishi, Yoshihiro Uto, Kei Ohkubo, Tadashi Shirai, Eiji Nakata, Hideko Nagasawa, Hitoshi Hori, Shunichi Fukuzumi, Toshihiko Ozawa, and Kazunori Anzai
    J. Clin. Biochem. Nutr., 41 (Supplement), 140 (2007).
  39. Effect of Methyl Substitution of Antioxidative Properties and Genotoxicity of Resveratrol
    Kiyoshi Fukuhara, Ikuo Nakanishi, Atsuko Matsuoka, Toshihiko Ozawa, Naoki Miyata, Nobuo Ikota, and Haruhiro Okuda
    J. Clin. Biochem. Nutr., 41 (Supplement), 155 (2007).
  40. Effect of Metal Ions on the Radical-Scavenging Rates of Hydroquinones
    Ikuo Nakanishi, Yoshihiro Uto, Kei Ohkubo, Tadashi Shirai, Eiji Nakata, Sushma Manda, Hideko Nagasawa, Hitoshi Hori, Kiyoshi Fukuhara, Haruhiro Okuda, Nobuo Ikota, Shunichi Fukuzumi, Kazunori Anzai, and Toshihiko Ozawa
    J. Pharm. Soc. Jpn., 128 (Suppl. 1), 71 (2008).
  41. Scavenging Reactions of Free Radicals by Propenylphenol Compounds
    Tomonori Kawashima, Ikuo Nakanishi, Yoshihiro Uto, Kei Ohkubo, Keiko Suzuki, Sushma Manda, Hideko Kanazawa, Kiyoshi Fukuhara, Haruhiro Okuda, Hideko Nagasawa, Hitoshi Hori, Shunichi Fukuzumi, Kazunori Anzai, Toshihiko Ozawa, and Nobuo Ikota
    "Proceeding of the 6th Meeting of Society of the Study of AOB (Antioxidant Biofactor)," (2008), pp.20-23.
  42. Structure-Activity Relationship in Radical-Scavenging Reactions of Naturally-Oriented Artepillin C Derivatives
    Ikuo Nakanishi, Yoshihiro Uto, Kei Ohkubo, Tomonori Kawashima, Sushma Manda, Ken-ichiro Matsumoto, Hitoshi Hori, Kiyoshi Fukuhara, Haruhiro Okuda, Nobuo Ikota, Shunichi Fukuzumi, Toshihiko Ozawa, and Kazunori Anzai
    Prog. Biochem. Biophys., 35 (Suppl), 290 (2008).
  43. Free Radical Reactions in an Aqueous Sample Caused by Heavy-Ion (Carbon) Beam Irradiation
    Ken-ichiro Matsumoto, Ikuo Nakanishi, Kazutoyo Endo, and Kazunori Anzai
    Free Radical Biol. Med., 45 (S1), S20 (2008).
  44. One-Step Hydrogen Atom Transfer in Radical-Scavenging Reactions by Artepillin C Derivatives Enhanced by Electron-Donating Groups
    Ikuo Nakanishi, Kei Ohkubo, Yoshihiro Uto, Tomonori Kawashima, Sushma Manda, Kiyoshi Fukuhara, Haruhiro Okuda, Hitoshi Hori, Nobuo Ikota, Shunichi Fukuzumi, Toshihiko Ozawa, and Kazunori Anzai
    Free Radical Biol. Med., 45 (S1), S63 (2008).
  45. Synthesis and Radical-Scavenging Activity of Vitamin E Derivatives Having a Basic Moiety
    Ikuo Nakanishi, Tomonori Kawashima, Haruko Yakumaru, Minako Nyui, Kei Ohkubo, Hideko Kanazawa, Kiyoshi Fukuhara, Haruhiro Okuda, Shunichi Fukuzumi, Toshihiko Ozawa, Nobuo Ikota, Kazunori Anzai
    "Advances in the Research of Vitamin E Volume XIII," Japanese Vitamin E Research Association, Japan (2009), pp.7-10.
  46. Radical-Scavenging Rates of Biosynthetic Precursors of Vitamin E and Their Acyclic Analogues
    Ikuo Nakanishi, Yoshihiro Uto, Kei Ohkubo, Tadashi Shirai, Eiji Nakata, Hideko Nagasawa, Hitoshi Hori, Kiyoshi Fukuhara, Haruhiro Okuda, Nobuo Ikota, Shunichi Fukuzumi, Toshihiko Ozawa, and Kazunori Anzai
    "Advances in the Research of Vitamin E Volume XIII," Japanese Vitamin E Research Association, Japan (2009), pp.83-87.
  47. Structure-Activity Relationship in Radical-Scavenging Reactions of Naturally-Oriented Artepillin C Derivatives
    Ikuo Nakanishi, Yoshihiro Uto, Kei Ohkubo, Tomonori Kawashima, Sushma Manda, Ken-ichiro Matsumoto, Hitoshi Hori, Kiyoshi Fukuhara, Haruhiro Okuda, Nobuo Ikota, Shunichi Fukuzumi, Toshihiko Ozawa, and Kazunori Anzai
    "XIV Biennial Meeting of the Society for Free Radical Research International," International Proceedings, Medimond, Italy (2009), pp.125-128.
  48. Development of Novel Scavengers against Reactive Oxygen Species and Free Radicals by Chemical Modification of Natural Antioxidants
    Ikuo Nakanishi
    Radiological Sciences, 52 (5), 17-19 (2009).
A W A R D S
  1. The SFRR Japan Award for Young Scientists (June 28, 2003) Society for Free Radical Research Japan (SFRR Japan), Tokyo, Japan
  2. SFRR Japan Young Investigator Award 2006 (August 18, 2006) 13th Biennial Congress of the Society for Free Radical Research International (SFRRI), Davos, Switzerland
  3. Poster Award (November 30, 2007) International Conference on Food Factors for Health Promotion (ICoFF2007), Kyoto, Japan
  4. SFRR Japan Young Investigator Award 2008 (October 21, 2006) The XIV Biennial Meeting of the Society for Free Radical Research International (14th SFRR), Beijing, China
DOCTORAL THESIS

"Base Catalysis in Electron Transfer Mechanisms"

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